TCO PEG Thiol, TCO-PEG-SH
TCO PEG Thiol, TCO-PEG-SH, MW 5000
TCO PEG Thiol, TCO PEG SH is a bifunctional TCO PEG derivative that has a terminal thiol group. TCO (transcyclooctene) group reacts with tetrazine group fast and efficiently while thiol (sulfhydryl group) can be used to react with maleimide, bind to gold surface and participate in many other reactions. The reaction of TCO and tetrazine is a bioorthogaonal reaction that enables the conjugation of two molecules in aqueous solution fast and efficiently. PEG TCO derivatives have excellent water solubility, possess fast kinetics and stability in aqueous buffer. They are one of the best pegylation reagents to modify proteins, peptides, antibodies, biopolymers and particles via copper free Click Chemistry reaction.
- Appearance: White solid;
- Solubility: Soluble in water, ethanol, DMSO, etc.;
- Reactivity: TCO reacts with tetrazine.
- Store at -20 0C; Desiccate; Avoid frequent thaw and freeze.