TCO PEG amine, TCO-PEG-NH2
TCO PEG amine, TOC PEG NH2, MW 5000
TCO PEG NH2 is a TCO PEG derivative that has an primary amine group. TCO (transcyclooctene) group reacts with tetrazine group fast and efficiently while primary amine group can be used to react with many other groups such COOH, NHS, isocyanate, etc. The reaction of TCO and tetrazine is a bioorthogaonal reaction that enables the conjugation of two molecules in aqueous solution fast and efficiently. PEG TCO derivatives have excellent water solubility, possess fast kinetics and stability in aqueous buffer. They are one of the best pegylation reagents to modify proteins, peptides, antibodies, biopolymers and particles via copper free Click Chemistry reaction.
- Appearance: White solid;
- Solubility: Soluble in water, ethanol, DMSO, etc.;
- Reactivity: TCO reacts with tetrazine.
- Store at -20 0C; Desiccate; Avoid frequent thaw and freeze.