Silane PEG Biotin Cat. No. PG2-BNSL-3k 3400 Da 100 mg修饰性聚乙二醇

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Silane PEG Biotin

Cat. No. PG2-BNSL-3k Silane PEG Biotin           Cat. No. PG2-BNSL-3k     3400 Da    100 mg
Specification 3400 Da
Unit Size 100 mg
Price $345.00


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Synonym: Silane PEG Biotin, Biotin PEG Silane, Silane polyethylene glycol biotin, Biotin polyethylene glycol Silane

Description:

Ethoxy or methoxyl silane functionalized polyethylene glycol Biotin, silane PEG Biotin (Biotin-PEG-Si) is one of Nanocs surface reactive PEG derivatives that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxyl silane. Biotin functional silane PEG is able to attached polyethylene glycol to various glass or metal surface biotin tag. Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development.

Physical Properties:

  • Form: Solid
  • Color: White
  • Reactive group: Triethoxysilane
  • Functional tag: Biotin
  • Solubility: Soluble in water
  • Purity: >95%
  • Applications: Surface modification

Storage Conditions:

  • Store at -20 0C. Desiccate. Silane PEG tends to hydrolyze from moisture. Avoid frequent thaw and frozen. USE ASAP.

Reaction Procedures:

Generally, silane PEG is first dissolved in a mixture of ethanol/water  or DMSO solution, then allow the solution to contact with oxidized glass or silica surface for 30 min to 2 hours. Under this condition, silane PEG should bind to the material covalently.

Materials Required:

  • Pegylation solution: Ethanol/water (w/w, 95%/5%);
  • Silane PEG stock solution, 10~50 mg/mL in pegylation solution, prepare in fresh.
  • Washing solution: Distilled water.

Reaction Steps:

  1. Dissolve targeted materials in Pegylation buffer.
  2. Add silane PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of silane PEG needed for optimal conjugation;
  3. Allow mixture agitates at room temperature for 30 min at room temperature or 2 hours at 4 -20 0C.
  4. Wash out unreacted materials either by distilled water.

References:

Click here to check hundreds of publications using Nanocs PEGs.

Documents
  • SDS
  • DataSheet

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