Maleimide PEG PFP, MAL-PEG-PFP
Nanocs Maleimide PEG PFP (Pentafluorophenyl) is a heterobifunctional PEG derivative that can react with both thiol and amine groups. Maleimide reacts with sulfhydryl groups at pH 6.5-7.5 to form stable thiol-ether bond while PFP reacts with amine groups at pH 7-9 to form stable aminde bond. Compared to other amine reactive linkers, PFP has higher reactivity yet with better stability in aqueous buffer. PFP reacts not only with primary amine, but also with secondary amine groups.
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.