Maleimide-PEG4-NHS Cat. No. M-P4S-1 5 mg修饰性聚乙二醇



Cat. No. M-P4S-1 Maleimide-PEG4-NHS           Cat. No. M-P4S-1         5 mg
Unit Size 5 mg
Price $385.00

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Nanocs SnapLink TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

  • Appearance: Off-white semi-solid or solid;
  • Reactivity: Reactive to sulfhydryl and amine groups;
  • Solubility: Soluble in DMSO or DMF.

Storage Conditions:

  • Store at -20 0C, desiccated. Avoid frequent thaw and freeze.