Polyethylene Glycol, HO-PEG-OH

Polyethylene Glycol, HO-PEG-OH

Amino PEG Amine, NH2-PEG-NH2

Description:

Amino functionalized polyethylene glycol (NH2-PEG-NH2) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Amino PEG Amine, NH2-PEG-NH2

Description:

Amino functionalized polyethylene glycol (NH2-PEG-NH2) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Carboxylic Acid PEG Acid, HOOC-PEG-COOH

Description:

Carboxyli acid functionalized polyethylene glycol (COOH-PEG-COOH) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

*Note: Structure showed here mainly represents the functional groups derived from PEG. Exact linker may not show. Contact us if you have any concern about the linker.

Carboxylic Acid PEG Acid, HOOC-PEG-COOH

Description:

Carboxyli acid functionalized polyethylene glycol (COOH-PEG-COOH) is a homobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

*Note: Structure showed here mainly represents the functional groups derived from PEG. Exact linker may not show. Contact us if you have any concern about the linker.

CDI-PEG-CDI

Amino PEG Acid, NH2-PEG-COOH

Synonym: Amine PEG acid, Acid PEG Amine, NH2-PEG-COOH, COOH-PEG-NH2

Description:

Amino PEG Acid (NH2-PEG-COOH) is one of  Nanocs reactive heterobifunctional PEG derivatives that have an amine group on one PEG end and a carboxylic acid group on the other PEG terminus. Amino PEG acid can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Form: Solid
• Color: White
• Solubility: Soluble in water
• Functional groups: Amine (-NH2) and acid (-COOH)
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C.

References:

Click here to see hundreds of publications using Nanocs PEGs.

Hydroxyl PEG amine, NH2-PEG-OH

Synonym: Hydroxyl PEG amine (free amine), HO-PEG-NH2, NH2-PEG-OH, Amino PEG Hydroxyl, Amine PEG hydroxyl

Description:

Hydroxyl PEG amine (HO-PEG-NH2) is one of Nanocs heterobifunctional PEG derivatives that have a hydroxyl group on one PEG end and a free amine group on the other PEG terminus. Hdyroxyl PEG amine can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Form: Semi-liquid
• Color: Amber
• Solubility: Soluble in water
• Functional groups: Amine, Hydroxyl
• Substitution purity: >95%

Storage Conditions:

• Store at -20 ⁰C. Avoid frequent thaw and freeze.

References:

Click here to check hundreds of publications using Nanocs PEGs.

NHS PEG COOH

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

NHS PEG COOH

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

NHS PEG OH

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Fmoc-NH-PEG-COOH

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Boc-NH-PEG-NHS

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Boc-NH-PEG-NHS

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Acryloyl-PEG-COOH

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Acryloyl PEG amine

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, dessiccated Protect from light. Avoid frequent thaw and freeze.

PEG Biotin, mPEG-Biotin

Description:

mPEG Biotin is one of Nanocs Biotin functionalized methoxypolyethylene glycol (mPEG-Biotin) derivatives that can bind to avidin or streptavidin with high affinity. Pegylated biotin is soluble in aqueous solution and it can be used directly in buffer without need adding any organic solvents. 

Physical Properties:

• Form: Solid
• Color: White to off-white
• Solubility: Soluble in water
• Functional ligand: Biotin
• Binding target: Avidin, streptavidin, neutravidin

Storage Conditions:

• Store at -20 ⁰C. Avoid frequent thaw and freeze.

PEG Biotin, mPEG-Biotin

Description:

mPEG Biotin is one of Nanocs Biotin functionalized methoxypolyethylene glycol (mPEG-Biotin) derivatives that can bind to avidin or streptavidin with high affinity. Pegylated biotin is soluble in aqueous solution and it can be used directly in buffer without need adding any organic solvents. 

Physical Properties:

• Form: Solid.
• Color: White to off-white
• Solubility: Soluble in water
• Functional ligand: Biotin
• Binding target: Avidin, streptavidin, neutravidin

Storage Conditions:

• Store at -20 ⁰C. Avoid frequent thaw and freeze.

Biotin-PEG-NHS, NHS PEG Biotin

Synonym: NHS PEG Biotin, Biotin PEG Succinimidyl ester, Biotin PEG3000 NHS, NHS PEG3000 Biotin

Description:

Biotin PEG NHS is one of Nanocs reactive PEG biotin reagents that can be used to label proteins, antibodies, small molecules or surfaces via their available amine groups. NHS reacts quickly with primary amine groups under alkaline pH to yield a stable amide bond. This reaction allows rapid attachement of biotin tag to targeted molecules or material surfaces. Resulted biotin tag can be easily detected with avidin or streptavidin. PEG linker between NHS and Biotin offers better water solubility, flexible linker structure and enhanced stability. 

Physical Properties:

• Form: Solid
• Color: White
• Solubility: Soluble in aqueous buffer
• Reactive group: NHS (succinimidyl ester)
• Reactive to: Primary amine group (-NH2)
• Applications: Biotin conjugation (Biotinylation)
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C. Desiccate. Avoid frequent thaw and freeze.

References:

Click here to check hundreds publications using Nanocs PEGs.