DBCO PEG2000 Silane

Cat. No. PG2-DBSL-2k Specification Unit Size 25 mg Price $385.00 Qty Add to Cart

Description:

DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction.  This reaction has excellent selectivity and biocompatibility, such that the complimentary reagents can form covalent bonds with richly functionalized biological systems. The Cu-free click reaction has been a powerful tool in catalyst-free bioconjugation. DBCO reagents posses fast kinetcs and stability in aqueous buffer and they can be used to label azide-modified biomolecules with high specificity and reactivity. 

Physical Properties:

• Yellow/pale-yellow solid or semi-solid;
• Soluble in DMSO or DMF;

Storage Conditions:

• Store at -20 ⁰C, desiccate. Avoid frequent thaw and frozen.

Copper-free Click Reaction Procedures:

Prepare the azide-containing sample in reaction buffer. Add DBCO conjugate to azide containing sample. Recommendation: Add 1 mole equivalent of limiting reagent to 1.5-3.0 mole equivalents of highest abundance reagent. Incubate the reaction at room temperature for 2-4 hours or 2-12 hours at 4 degree celcius. The reaction is now ready for purification.

DBCO PEG2000 Glucose

Cat. No. PG2-DBGLU-2k Specification Unit Size 25 mg Price $485.00 Qty Add to Cart

Description:

DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction.  This reaction has excellent selectivity and biocompatibility, such that the complimentary reagents can form covalent bonds with richly functionalized biological systems. The Cu-free click reaction has been a powerful tool in catalyst-free bioconjugation. DBCO reagents posses fast kinetcs and stability in aqueous buffer and they can be used to label azide-modified biomolecules with high specificity and reactivity. 

Physical Properties:

• Yellow/pale-yellow solid or semi-solid;
• Soluble in DMSO or DMF;

Storage Conditions:

• Store at -20 ⁰C, desiccate. Avoid frequent thaw and frozen.

Copper-free Click Reaction Procedures:

Prepare the azide-containing sample in reaction buffer. Add DBCO conjugate to azide containing sample. Recommendation: Add 1 mole equivalent of limiting reagent to 1.5-3.0 mole equivalents of highest abundance reagent. Incubate the reaction at room temperature for 2-4 hours or 2-12 hours at 4 degree celcius. The reaction is now ready for purification.

Maleimidoacetic acid NHS

Cat. No. M-C2S-1 Specification Unit Size 100 mg Price $385.00 Qty Add to Cart

Description:

Nanocs maleidoacetic acid NHS (Maleimide-C2-NHS) is an amine and sulfhydryl crosslinker with a short C2 space arm between maleimide and NHS. This crossliker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%
• Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

• Store at -20 ⁰C, Desiccate.

ITO Coated Glass Slides, 25x75x1.1 mm

Cat. No. IT100-111-25 Specification 100 ohm/sq Unit Size 20 slides Price $385.00 Qty Add to Cart

ITO (Inidum Tin Oxide) and FTO (fluorine doped tin oxide) Coated Glass Slides

ITO (Indium Tin Oxide) and FTO coated glass slides provided from Nanocs were made by coating ITO or FTO to one side of soda lime glass. These ITO and/or FTO coated glass, also called transparent conductive glass (TCO), come with different surface resistivity from 5 ohm/sq to 100 ohm/sq, with thickness from 0.5 mm to 2.2 mm. ITO and FTO coated glass has been used in LCD/OLED devices and many other devices requiring high electrical conductivity and good optical transmission. Our ITO/FTO coated glass has excellent surface roughness around +-5 nm. Thickness of our ITO or FTO coating ranges from 50 nm to 700 nm depends on their surface resistivity. Optical transmission of these ITO coated glass is over 85% in the visible range.

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Nanocs ITO/FTO Glass Specifications:

• Surface resistivity: 5~100 ohm/sq, see individual product label;
• Glass thickness: 0.55 mm, 1.1 mm or 2.2 mm;
• ITO thickness: 30~600 nm depends on ITO surface resistivity:
• Optical transmission: 83% to 90%;
• ITO glass size: 1 cm to 10 cm, customer size available upon request.

Maleimidopropionic acid NHS

Cat. No. M-C3S-1 Specification Unit Size 100 mg Price $385.00 Qty Add to Cart

d primary amines, therefore, the reaction requires neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%
• Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

• Store at -20 ⁰C, Desiccate.

4-Maleimidobutyric acid NHS, GMBS

Cat. No. M-C4S-1 Specification Unit Size 50 mg Price $385.00 Qty Add to Cart

Description:

Nanocs maleidobutyric acid NHS, also called GMPS, is an amine and sulfhydryl crosslinker with a short space arm between maleimide and NHS. This crossliker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%
• Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

• Store at -20 ⁰C. Desiccate.

6-Maleimidocaproic acid NHS, EMCS

Cat. No. M-C6S-1 Specification Unit Size 50 mg Price $385.00 Qty Add to Cart

s neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%
• Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

• Store at -20 ⁰C, Desiccate.

6-maleimidocaproic acid

Cat. No. M-6C-1 Specification Unit Size 100 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink maleimide acid is an amine and sulfhydryl reactive crosslinker. This crossliker is non-cleavable and water soluble. It contains a carboxylic acid that can be activated with EDC and reacts toward primary amine groups. The maleimide group reacts with available sulfhydryl groups from naturally occurring or mutagenically derived cysteine residues at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C, dessiccated. Avoid frequent thaw and freeze.

MBS, Maleimidobenzoyl NHS

Cat. No. M-BS-1 Specification Unit Size 5 mg Price $325.00 Qty Add to Cart

Description:

Nanocs m-Maleimidobenzyol N-hydroxysccinimide, also called MBS, is an aromatic, amine and sulfhydryl crosslinker with a short space arm between maleimide and NHS. This crossliker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. The maleimide group reacts with available –SH groups from naturally occurring or mutagenically derived cysteine residues. Maleimide groups react with sulfhydryl groups at pH 6.5~7.5 at room temperature to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%
• Solubility: Soluble in DMF or DMSO; Not soluble in water;

Storage Conditions:

• Store at -20 ⁰C. Desiccate. Avoid frequent thaw and freeze.

Maleimide-PEG4-NHS

Cat. No. M-P4S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink ^TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white semi-solid or solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMSO or DMF.

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

Maleimide-PEG12-NHS

Cat. No. M-P12S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink ^TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white semi-solid or solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMSO or DMF.

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

Maleimide-PEG23-NHS

Cat. No. M-P23S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink ^TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white semi-solid or solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMSO or DMF.

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

Maleimide-PEG45-PFP

Cat. No. M-P45PF-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG NHS is a pegylated, amine and sulfhydryl reactive crosslinker. This crossliker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C, dessiccated. Avoid frequent thaw and freeze.

Maleimide-PEG75-PFP

Cat. No. M-P75PF-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink maleimide PEG NHS is a pegylated, amine and sulfhydryl reactive crosslinker. This crossliker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C, dessiccated. Avoid frequent thaw and freeze.

SMCC-PEG4-NHS

Cat. No. M2-P4S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

SMCC-PEG12-NHS

Cat. No. M2-P12S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

SMCC-PEG23-NHS

Cat. No. M2-P23S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

SMCC-PEG45-NHS

Cat. No. M2-P45S-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

2-Maleimidoethyl amine

Cat. No. M-C2A-1 Specification CAS# 146474-00-2 Unit Size 5 mg Price $325.00 Qty Add to Cart

Description:

Nanocs SnapLink maleimide amine is a heterobifunctional crosslinker. This crosslinker contains a primary amine group that can be reacted with a variety of amine reactive groups, such as NHS. The maleimide group reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid;
• Purity: >95%

Storage Conditions:

• Store at -20 ⁰C, dessiccated. Avoid frequent thaw and freeze.

Maleimide-PEG4-NH2

Cat. No. M-P4A-1 Specification Unit Size 5 mg Price $385.00 Qty Add to Cart

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) amine is a heterobifunctional crosslinker that can react with sulfhydryl and amien reactive groups, such as NHS ester. This crosslinker contains a sulfhydryl reactive maleimide group and a primary amine group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the cyclohexane maleimide PEG amine a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. Maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and carboxylic groups;
• Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccate. Avoid frequent thaw and freeze.