Alkyne PEG acid, ALK-PEG-COOH
Alkyne functionalized polyethylene glycol (Alk-PEG-X) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials via Click Chemistry. Alkyne group can react with azide in aqueous solution catalyzed by copper. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
- Off-white/white solid or viscous liquid depends on molecule weight;
- Soluble in regular aqeous solution as well as most organic solvents;
- Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.