DSPE PEG Azide, DSPE-PEG-N3
1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Nanocs azide PEG DSPE products can be used to prepare pegylated liposome using Click Chemistry. Azide reacts readily with alkyne or cycloocytne in aqueous solution with or without copper catalyst. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.
- White/off-white solid or semi-solid depends on molecule weight;
- Soluble in warm aqeous solution as well as most organic solvents;
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.