N-ethylmaleimide, NEM Cat. No. M-C2-2 CAS# 128-53-0 5 g修饰性聚乙二醇

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

N-ethylmaleimide, NEM

Cat. No. M-C2-2
Specification CAS# 128-53-0
Unit Size 5 g
Price $685.00


Qty Add to Cart

Description:

N-ethylmaleimide (NEM) is a water soluble, thiol reactive maleimide that can be used to modify protein cysteineresidues. Maleimide reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds. NEM has been used for protein Acyl-RAC assayN-ethylmaleimide is a sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 µM) in pancreatic duct cells. N-ethylmaleimide Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. NEM stimulates arachidonic acid release through activation of PLA2 in endothelial cells. As a commonly used sulfhydryl alkylating reagent, NEM has been used for blocking sulfhydryl containing reagents which interfere with glucose oxidase assays. Inactivates NADP-dependent isocitrate dehydrogenase. Endonuclease inhibitor. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei.

Physical Properties:

  • Appearance: Off-white/faint yellow solid
  • Mol Wt: 125.13
  • CAS No: 128-53-0
  • Purity: >98%

Storage Conditions:

  • Store at -20 0C. 
Related Products
AR-NTA-1 , Ni-NTA His-select Agarose Beads
AR-SS-1 , Agarose, S3 high capacity acyl-RAC capture beads
AR-SR-1 , Thiol reducing Agarose beads