SPDP (Succinimidyl 3-[2-pyridyldithio] propionate) Cat. No. SPD01 20 mg修饰性聚乙二醇

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SPDP (Succinimidyl 3-[2-pyridyldithio] propionate)

Cat. No. SPD01 SPDP (Succinimidyl 3-[2-pyridyldithio] propionate)           Cat. No. SPD01         20 mg
Specification
Unit Size 20 mg
Price $325.00


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SPDP Crosslinker Description:

Nanocs SnapLinkTM SPDP crosslinker, NSuccinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups.

In addition to above hydrophobic SPDP crosslinker, Nanocs also offer water-soluble SPDP crosslinker either with sulfonated NHS (Sulfo-SPDP) or Pegylated SPDP crosslinker, such as our PEG OPSS products. These SPDP crosslinkers are heterobifunctional and thiol cleavable crosslinkers.

SPDP Crosslinker Physical Properties:

  • Appearance: Off-white/white solid;
  • Reactive groups: NHS ester and pyridyldithiol;
  • Reactive towards: amino (amine) and sulfhydryl (thiol) groups;
  • SPDP crosslinker is membrane permeable;
  • Solubility: Soluble in DMF or DMSO;

SPDP Applications:

  • Adding thiol/sulfhydryl groups to proteins, antibodies or other molecules by reacting with amine groups;
  • Reversible crosslinking of proteins or other molecules;

SPDP Storage Conditions:

  • Store at -20 0C, desicate. Avoid frequent thaw and freeze.
Related Products
PG1-OS-5k , Ortho-pyridine disulfide PEG, mPEG-OPSS