Maleimide-PEG12-NHS

Description:

Nanocs SnapLink ^TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white semi-solid or solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMSO or DMF.

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

Maleimide-PEG23-NHS

Description:

Nanocs SnapLink ^TMmaleimide PEG NHS is a pegylated, amine and sulfhydryl reactive cross-linker. This cross-linker is non-cleavable and water soluble. It contains an amine reactive, NHS ester and a sulfhydryl reactive maleimide group linked with polyethylene glycol of different length. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. NHS esters react with deprotonated primary amines in pH 7-9. The maleimide group reacts with thiol groups at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white semi-solid or solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMSO or DMF.

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

SMCC-PEG23-NHS

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

SMCC-PEG45-NHS

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) is an amine and sulfhydryl reactive crosslinker. This crosslinker is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the maleimide NHS a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/brownish solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and amine groups;
• Solubility: Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccated. Avoid frequent thaw and freeze.

Maleimide-PEG4-NH2

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) amine is a heterobifunctional crosslinker that can react with sulfhydryl and amien reactive groups, such as NHS ester. This crosslinker contains a sulfhydryl reactive maleimide group and a primary amine group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the cyclohexane maleimide PEG amine a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. Maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and carboxylic groups;
• Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccate. Avoid frequent thaw and freeze.

Maleimide-PEG12-NH2

Description:

Nanocs SnapLink^TM pegylated succinimidyl cyclohexane Maleimide (SMCC) amine is a heterobifunctional crosslinker that can react with sulfhydryl and amien reactive groups, such as NHS ester. This crosslinker contains a sulfhydryl reactive maleimide group and a primary amine group bridged with PEG arm. The hydrophilic polyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the crosslinked molecules , thus reducing aggregation of labeled proteins in solution. The PEG spacer arm also gives the cyclohexane maleimide PEG amine a long and flexible structure to minimize steric hindrance for its reaction to other molecues. Compared to other maleimide NHS ester, SMCC has higher stability in aqueous solution because of its cyclohexane bridge. Maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties:

• Appearance: Off-white/white solid or semi-solid;
• Reactivity: Reactive to sulfhydryl and carboxylic groups;
• Soluble in DMF or DMSO;

Storage Conditions:

• Store at -20 ⁰C, desiccate. Avoid frequent thaw and freeze.

N-ethylmaleimide, NEM

Description:

N-ethylmaleimide (NEM) is a water soluble, thiol reactive maleimide that can be used to modify protein cysteineresidues. Maleimide reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds. NEM has been used for protein Acyl-RAC assay. N-ethylmaleimide is a sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 µM) in pancreatic duct cells. N-ethylmaleimide Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. NEM stimulates arachidonic acid release through activation of PLA2 in endothelial cells. As a commonly used sulfhydryl alkylating reagent, NEM has been used for blocking sulfhydryl containing reagents which interfere with glucose oxidase assays. Inactivates NADP-dependent isocitrate dehydrogenase. Endonuclease inhibitor. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei.

Physical Properties:

• Appearance: Off-white/faint yellow solid
• Mol Wt: 125.13
• CAS No: 128-53-0
• Purity: >98%

Storage Conditions:

• Store at -20 ⁰C. 

ITO Coated Glass Slides, 25x75x1.1 mm

ITO (Inidum Tin Oxide) and FTO (fluorine doped tin oxide) Coated Glass Slides

ITO (Indium Tin Oxide) and FTO coated glass slides provided from Nanocs were made by coating ITO or FTO to one side of soda lime glass. These ITO and/or FTO coated glass, also called transparent conductive glass (TCO), come with different surface resistivity from 5 ohm/sq to 100 ohm/sq, with thickness from 0.5 mm to 2.2 mm. ITO and FTO coated glass has been used in LCD/OLED devices and many other devices requiring high electrical conductivity and good optical transmission. Our ITO/FTO coated glass has excellent surface roughness around +-5 nm. Thickness of our ITO or FTO coating ranges from 50 nm to 700 nm depends on their surface resistivity. Optical transmission of these ITO coated glass is over 85% in the visible range.

Nanocs ITO/FTO Glass Specifications:

• Surface resistivity: 5~100 ohm/sq, see individual product label;
• Glass thickness: 0.55 mm, 1.1 mm or 2.2 mm;
• ITO thickness: 30~600 nm depends on ITO surface resistivity:
• Optical transmission: 83% to 90%;
• ITO glass size: 1 cm to 10 cm, customer size available upon request.

ITO Coated PET Film, 25×75 mm

ITO (Inidum Tin Oxide) and FTO (fluorine doped tin oxide) Coated PET Plastic Film

ITO (Indium Tin Oxide) and FTO coated PET plastic film provided from Nanocs were made by coating ITO or FTO to one side of PET film. These ITO coated plastic film comes with different surface resistivity from 30 ohm/sq to 100 ohm/sq, with thickness around 0.17 mm. ITO coated PET film has been used in LCD/OLED devices and many other devices requiring high electrical conductivity and good optical transmission. Our ITO coated PET has excellent surface roughness around +-5 nm. Thickness of our ITO coating ranges from 50 nm to 700 nm depends on their surface resistivity. Optical transmission of these ITO coated plastic film is over 85% in the visible range.

Nanocs ITO Coated PET Film Specifications:

• Surface resistivity: 5~100 ohm/sq, see individual product label;
• PET plastic thickness: 0.17~0.22 mm;
• ITO thickness: 30~600 nm depends on ITO surface resistivity:
• Optical transmission: 83% to 90%;
• ITO PET size: 1 cm to 10 cm, customer size available upon request.

ITO Coated PET Film, 25×75 mm

ITO (Inidum Tin Oxide) and FTO (fluorine doped tin oxide) Coated PET Plastic Film

ITO (Indium Tin Oxide) and FTO coated PET plastic film provided from Nanocs were made by coating ITO or FTO to one side of PET film. These ITO coated plastic film comes with different surface resistivity from 30 ohm/sq to 100 ohm/sq, with thickness around 0.17 mm. ITO coated PET film has been used in LCD/OLED devices and many other devices requiring high electrical conductivity and good optical transmission. Our ITO coated PET has excellent surface roughness around +-5 nm. Thickness of our ITO coating ranges from 50 nm to 700 nm depends on their surface resistivity. Optical transmission of these ITO coated plastic film is over 85% in the visible range.

Nanocs ITO Coated PET Film Specifications:

• Surface resistivity: 5~100 ohm/sq, see individual product label;
• PET plastic thickness: 0.17~0.22 mm;
• ITO thickness: 30~600 nm depends on ITO surface resistivity:
• Optical transmission: 83% to 90%;
• ITO PET size: 1 cm to 10 cm, customer size available upon request.

FTO Coated Glass Slides, 25x75x2 mm

ITO (Inidum Tin Oxide) and FTO (fluorine doped tin oxide) Coated Glass Slides

ITO (Indium Tin Oxide) and FTO coated glass slides provided from Nanocs were made by coating ITO or FTO to one side of soda lime glass. These ITO and/or FTO coated glass, also called transparent conductive glass (TCO), come with different surface resistivity from 5 ohm/sq to 100 ohm/sq, with thickness from 0.5 mm to 2.2 mm. ITO and FTO coated glass has been used in LCD/OLED devices and many other devices requiring high electrical conductivity and good optical transmission. Our ITO/FTO coated glass has excellent surface roughness around +-5 nm. Thickness of our ITO or FTO coating ranges from 50 nm to 700 nm depends on their surface resistivity. Optical transmission of these ITO coated glass is over 85% in the visible range.

Nanocs ITO/FTO Glass Specifications:

• Surface resistivity: 5~100 ohm/sq, see individual product label;
• Glass thickness: 0.55 mm, 1.1 mm or 2.2 mm;
• ITO thickness: 30~600 nm depends on ITO surface resistivity:
• Optical transmission: 83% to 90%;
• ITO glass size: 1 cm to 10 cm, customer size available upon request.

Epoxy Functional Glass Slides

Epoxide Functional Glass Slides

Description

Epoxide functionalized glass slides are one of Nanocs premier functional glass products. Nanocs provides various surface functionalized glass slides and coverslips that can be used to attach biomolecules on top of them. Functional groups and coatings include amine, carboxylic acid, aldehyde, epoxide, biotin, streptavidin, NTA, maleimide, disulfide, azide, alkyne, as well as poly-D-lysine and poly-L-lysine. Nanocs glass slides and coverslips were fabricated with unique coating technologies to ensure their high reactivity, uniformity and low non-specific absorption. These glass slides and coverslips can be used for microarray fabrication, cell culture growth and various confocal microscope work.

Specifications:

• Surface functionality: Epoxy;
• Glass size: 25x75x1.1 mm;
• Epoxy density: 50~100 umol Epoxide/cm2.

Biotin coated glass slides

Biotin Functional Glass Slides

Description

Biotin functionalized glass slides are one of Nanocs premier functional glass products. Nanocs provides various surface functionalized glass slides and coverslips that can be used to attach biomolecules on top of them. Functional groups and coatings include amine, carboxylic acid, aldehyde, epoxide, biotin, streptavidin, NTA, maleimide, disulfide, azide, alkyne, as well as poly-D-lysine and poly-L-lysine. Nanocs glass slides and coverslips were fabricated with unique coating technologies to ensure their high reactivity, uniformity and low non-specific absorption. These glass slides and coverslips can be used for microarray fabrication, cell culture growth and various confocal microscope work.

Specifications:

• Surface functionality: Biotin;
• Glass size: 25x75x1.1 mm;
• Biotin density: 50~100 umol biotins/cm2.

Amino Functional Coverslips

NTA coated Coverslips

Coverslips, PEG acid coated

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, DPPE

1,2-Diphytanoyl-sn-glycero-3-phophoethanolamine

1-Lauroyl-rac-glycerol

1,2-Dimyristoyl-sn-glycerol